Tetrapeptide-29 Argininamide

What is Tetrapeptide-29 Argininamide?

Tetrapeptide-29 Argininamide is a synthetically produced oligopeptide composed of four amino acids, with the C-terminal modified as argininamide. This chemical structure mimics fragments of natural proteins found in the skin. It falls under the category of conditioning agents in cosmetic formulations, commonly incorporated into serums, creams, and lotions targeting facial care. In products, it functions by interacting with the skin's surface or upper layers, potentially aiding in maintaining skin barrier integrity and hydration balance through molecular signaling or humectant-like properties. Derived entirely from laboratory synthesis using amino acid building blocks, it avoids botanical sources, ensuring consistency and purity in cosmetic applications. Its use aligns with trends in peptide technology for gentle, non-invasive skin support.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Benefits

Acts as a skin conditioning agent to support moisture retention.

Presents low comedogenic rating, suitable for acne-prone skin.

Contributes to formulations with overall low hazard profiles.

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
Individuals incorporating peptides into daily skincare routines.
People with known allergies to peptides or amino acid derivatives.
Those with normal to dry skin seeking conditioning ingredients.
Those experiencing irritation from similar synthetic ingredients.
Users preferring low-risk additives in anti-aging products.
Individuals preferring entirely natural or botanical-based skincare.

Safety Notes

  • Considered low hazard based on available assessments.
  • Patch testing recommended for sensitive skin types.

Frequently Asked Questions about Tetrapeptide-29 Argininamide

What is Tetrapeptide-29 Argininamide?

A lab-made tetrapeptide used as a skin conditioning agent in skincare products.

Is it safe for daily use?

It has a low hazard rating and low comedogenic potential per assessments.

What products contain it?

Commonly found in serums, creams, and lotions for facial care.