Sodium Palmitoyl Proline

What is Sodium Palmitoyl Proline?

Sodium Palmitoyl Proline is the sodium salt of N-palmitoyl-L-proline, combining proline—an amino acid present in skin proteins—with palmitic acid, a saturated fatty acid from vegetable sources. Classified as a skin conditioning agent, it appears in moisturizers, lotions, and cleansing products. It functions by creating a lightweight film on the skin to aid moisture retention and improve texture, while its surfactant-like properties help blend oil and water phases for better product stability and application. This ingredient supports skin comfort by softening the surface without heaviness, making it suitable for various formulations targeting hydration and suppleness.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Roles in Formulation

This ingredient serves the following purposes in cosmetic formulations:

Skin conditioning agent
Maintains skin softness, smoothness, and flexibility.

Benefits

Enhances skin softness and smoothness

Supports skin flexibility and comfort

Contributes to non-comedogenic product designs

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
People with dry or rough skin
Those allergic to amino acid derivatives
Individuals seeking lightweight moisture
People sensitive to fatty acid salts
Users preferring mild conditioning agents
Individuals prone to rare hypersensitivities

Safety Notes

  • Low overall hazard potential
  • Non-comedogenic with rating of 0

Frequently Asked Questions about Sodium Palmitoyl Proline

What does Sodium Palmitoyl Proline do in skincare?

It acts as a skin conditioning agent to maintain softness, smoothness, and flexibility.

Is Sodium Palmitoyl Proline safe for sensitive skin?

It has low hazard and irritation potential, suitable for most skin types.

Does it cause breakouts?

No, it carries a comedogenic rating of 0.