Sodium Dextran Sulfate

What is Sodium Dextran Sulfate?

Sodium Dextran Sulfate is the sodium salt of sulfated dextran, a branched polysaccharide produced through bacterial fermentation of sucrose and subsequently chemically modified by sulfation. This water-soluble polymer belongs to the class of anionic polysaccharides commonly employed in skincare products such as serums, gels, creams, and suspensions. It functions primarily by interacting with water molecules to form a three-dimensional network, which increases the overall viscosity of the formulation. This network traps and evenly disperses insoluble components like pigments, exfoliating beads, or active ingredients, preventing them from settling at the bottom. In gel-based products, it builds structure for better spreadability and stability during storage. Its mild anionic nature also aids in maintaining emulsion integrity without altering pH significantly, making it suitable for lightweight, transparent formulations where clarity and uniformity are essential.

Comedogenic Rating 0/5 Low risk of clogging pores

EWG Safety Rating 1 View on EWG →

Roles in Formulation

This ingredient serves the following purposes in cosmetic formulations:

Suspending agent

Keeps insoluble particles (pigments, beads, actives) evenly dispersed by increasing viscosity or forming a network, preventing settling and separation.

Gel forming

Builds a gel network to increase viscosity and structure, improving suspension, spread, and stability in serums, gels, and some emulsions.

Viscosity controlling agent

Adjusts thickness to the desired level for stability and usability, improving dispensing, suspension, and texture across many formulation types.

Benefits

Helps maintain even distribution of pigments and particles for consistent product performance.

Enhances texture and spreadability in gels and serums for smoother application.

Supports formulation stability, preventing separation over time.

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit	Who Should Avoid
Users of pigmented or particle-containing products seeking uniform application.	Those with known sensitivities to sulfated polysaccharides.
Individuals preferring lightweight gels and serums with stable consistency.	Individuals preferring sulfate-free formulations on principle.
People with routine skincare needs for reliable, non-settling formulas.	Users of minimalist products avoiding synthetic polymers.

Safety Notes

Rated low hazard by environmental working group assessments.
Non-comedogenic, unlikely to clog pores.

Frequently Asked Questions about Sodium Dextran Sulfate

What products commonly contain Sodium Dextran Sulfate?

Found in serums, gels, creams, and suspensions with pigments or beads for stability.

Is Sodium Dextran Sulfate comedogenic?

It has a comedogenic rating of 0, indicating low likelihood of pore clogging.

Does it affect skin sensitivity?

Generally considered low irritation potential in cosmetic use.