Sh-Oligopeptide-2

What is Sh-Oligopeptide-2?

Sh-Oligopeptide-2 is a synthetically produced oligopeptide designed to replicate a portion of human insulin-like growth factor 1 (IGF-1), a naturally occurring protein involved in cell growth. Created through recombinant DNA technology using microorganisms such as yeast or bacteria, it consists of a short sequence of amino acids. In cosmetics, it functions as a skin conditioning agent, commonly found in anti-aging serums, creams, and treatments targeting mature skin. It operates by interacting with cell surface receptors on fibroblasts and keratinocytes, signaling pathways that promote cellular proliferation and matrix production. This mechanism aims to bolster skin structure and resilience. Valued for its targeted action at low levels, it integrates into formulations to enhance texture and vitality without compromising tolerability.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Benefits

Supports fibroblast activity for firmer skin appearance

Encourages keratinocyte renewal for smoother texture

Aids in maintaining skin's natural barrier resilience

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
Individuals with mature or thinning skin
Those with known peptide sensitivities
Those seeking texture refinement
Individuals prone to allergic reactions
People with environmentally stressed skin
People using products with untested biotech ingredients

Safety Notes

  • Rated low hazard by safety databases
  • Non-comedogenic with minimal irritation reports

Frequently Asked Questions about Sh-Oligopeptide-2

What is Sh-Oligopeptide-2?

A recombinant oligopeptide mimicking human IGF-1, used as a skin conditioner in anti-aging products.

Is it safe for daily use?

Safety assessments indicate low hazard potential for topical cosmetic application.

Does it clog pores?

Rated non-comedogenic, suitable for acne-prone skin.