Sh-Oligopeptide-1

What is Sh-Oligopeptide-1?

Sh-Oligopeptide-1 is a synthetic oligopeptide engineered to replicate the structure of human epidermal growth factor (EGF), a naturally occurring protein consisting of 53 amino acids. It is produced through recombinant DNA technology, typically using yeast or bacterial hosts, ensuring a consistent, high-purity form free from animal or human sources. In cosmetic formulations, it serves primarily as a skin conditioning agent in anti-aging serums, creams, and masks. Functionally, it binds to EGF receptors on the surface of skin cells like keratinocytes and fibroblasts, triggering intracellular pathways that influence cell proliferation, migration, and protein synthesis. This action aligns with the skin's innate repair mechanisms, aiding in maintaining barrier integrity and texture in topical applications.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Benefits

Supports skin cell signaling for renewal processes

May contribute to smoother skin appearance

Assists in preserving skin firmness and elasticity

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
Individuals noticing early aging signs
Persons with known peptide sensitivities
People seeking enhanced skin texture
Individuals advised against growth factor use
Those with environmentally stressed skin
Those with compromised skin barriers

Safety Notes

  • Low hazard rating from safety assessments
  • Non-comedogenic with zero rating

Frequently Asked Questions about Sh-Oligopeptide-1

What is Sh-Oligopeptide-1?

A synthetic peptide matching human epidermal growth factor, made via recombinant DNA for skin conditioning.

Is it safe for daily use?

Safety reviews rate it low hazard with minimal irritation concerns in cosmetics.

What skin types suit it?

Suitable for most, especially aging or dull skin, but patch test if sensitive.