Rh-Polypeptide-1

What is Rh-Polypeptide-1?

Rh-Polypeptide-1 is a synthetic polypeptide created through recombinant DNA technology in microorganisms, replicating the structure of human basic fibroblast growth factor (bFGF or FGF-2), a naturally occurring protein. It belongs to the category of biotech-derived active ingredients commonly found in high-end anti-aging serums, creams, and treatments targeting facial skin. In formulations, it acts as a signaling molecule that binds to specific receptors on fibroblasts and other skin cells, potentially encouraging cellular processes involved in maintaining skin structure, such as proliferation and matrix component synthesis. This function positions it as a skin conditioning agent, often incorporated at low levels to enhance product efficacy without altering texture or stability.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Benefits

Supports skin conditioning for smoother texture.

Associated with firmness in mature skin formulations.

Non-comedogenic, suitable for daily use.

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
Individuals with aging skin seeking conditioning support.
People with known peptide sensitivities.
Those using anti-aging serums and creams.
Those preferring fully natural ingredient lists.
Users looking for non-pore-clogging ingredients.
Individuals allergic to biotech-derived proteins.

Safety Notes

  • Rated low hazard by safety assessors.
  • Minimal risk of pore clogging.

Frequently Asked Questions about Rh-Polypeptide-1

What is Rh-Polypeptide-1?

A lab-made peptide copying human fibroblast growth factor, used in anti-aging skincare for cell signaling.

Is Rh-Polypeptide-1 safe for skin?

It has a low hazard rating and is non-comedogenic, suitable for most topical uses.

What skin types suit Rh-Polypeptide-1?

Best for aging or dry skin in conditioning products; test if sensitive.