Polyglyceryl-2 Isopalmitate/Sebacate

What is Polyglyceryl-2 Isopalmitate/Sebacate?

Polyglyceryl-2 Isopalmitate/Sebacate is a non-ionic emulsifier synthesized from polyglycerol-2, a polymer of glycerol often sourced from vegetable oils, esterified with isopalmitic acid (branched palmitic acid from palm) and sebacic acid (from castor oil). It belongs to the polyglyceryl ester family, favored in natural and eco-friendly cosmetics. In formulations, it functions by reducing surface tension at oil-water interfaces, forming stable micelles or emulsions that prevent separation. This makes it ideal for lightweight cleansers, micellar waters, lotions, and makeup removers, where it aids gentle cleansing and even distribution without heavy residues. Its branched structure enhances mildness and solubility in water-based systems.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Roles in Formulation

This ingredient serves the following purposes in cosmetic formulations:

Surfactant
Lowers surface tension to enable cleansing, emulsifying, and foaming; central to shampoos, body washes, and many emulsions and micellar systems.
Emulsifying agent
Enables stable mixing of oil and water phases by forming an interfacial film, helping create lotions, creams, and cleansers with consistent texture.

Benefits

Supports stable blending of oils and water for consistent product textures.

Promotes effective yet mild cleansing in washes and micellar solutions.

Helps create lightweight formulas suitable for daily skincare routines.

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
People with sensitive skin seeking gentle surfactants in cleansers.
Individuals with rare allergies to polyglycerol or sebacic acid derivatives.
Those preferring natural-derived emulsifiers in lotions and creams.
Those sensitive to palm-derived ingredients, despite low irritation risk.
Users of micellar waters or emulsion-based products for smooth application.
People preferring completely anhydrous or oil-only formulations.

Safety Notes

  • Rated low hazard by safety assessments, suitable for broad use.
  • Non-comedogenic, unlikely to clog pores in typical concentrations.

Frequently Asked Questions about Polyglyceryl-2 Isopalmitate/Sebacate

What does it do in skincare?

It emulsifies oils and water, stabilizing cleansers and lotions for better performance.

Is it safe for sensitive skin?

Yes, it's considered mild with low irritation potential from safety reviews.

Where is it commonly used?

Found in micellar waters, body washes, and emulsion creams for texture stability.