Palmitoyl Tetrapeptide-10

What is Palmitoyl Tetrapeptide-10?

Palmitoyl Tetrapeptide-10 is a laboratory-created peptide ingredient featuring a tetrapeptide sequence esterified with palmitic acid, a common fatty acid that improves lipid solubility and skin barrier penetration. It falls under the cell-communicating peptide category in cosmetics, commonly incorporated into serums, creams, and lotions for facial care. This ingredient works by emulating natural peptide signals in the skin's extracellular matrix, interacting with fibroblasts to support conditioning processes. Its design allows it to deliver targeted communication to skin cells without relying on botanical extracts or harsh actives, making it suitable for daily-use formulations focused on maintaining skin's structural balance. Authoritative databases like CosIng classify it strictly as a skin conditioning agent, highlighting its role in product texture and mild performance enhancement.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Benefits

Provides skin conditioning in formulations

Low comedogenic rating supports clearer skin use

Gentle profile suitable for regular application

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
Individuals incorporating conditioning peptides
People with known peptide sensitivities
Users of anti-aging moisturizers
Those experiencing reactions to fatty acid derivatives
Those preferring low-hazard cosmetic additives
Users avoiding synthetic peptides

Safety Notes

  • Considered low hazard by safety assessments
  • Non-comedogenic for pore-friendly routines

Frequently Asked Questions about Palmitoyl Tetrapeptide-10

What is Palmitoyl Tetrapeptide-10?

A synthetic tetrapeptide linked to palmitic acid, used as a skin conditioner in cosmetics.

Is it safe for daily use?

Rated low hazard with no comedogenic concerns, suitable for most routines.

What role does it play in products?

Enhances conditioning via cell signaling mimicry for skin maintenance.