Palmitoyl Myristyl Serinate

What is Palmitoyl Myristyl Serinate?

Palmitoyl Myristyl Serinate is a synthetically derived ester formed from palmitic acid, myristyl alcohol, and the amino acid serine. Classified as an emollient and skin-conditioning agent, it structurally resembles ceramides, the lipids naturally present in the skin's outermost layer. In cosmetic formulations such as moisturizers, creams, and lotions, it works by embedding into the intercellular spaces of the stratum corneum, aiding in the reinforcement of the skin's lipid barrier. This function helps formulations spread smoothly while contributing to the maintenance of skin's moisture balance and suppleness. Developed to replicate human skin lipids, it supports product efficacy in hydration-focused regimens without altering pH or causing disruption.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Roles in Formulation

This ingredient serves the following purposes in cosmetic formulations:

Skin conditioning agent
Maintains skin softness, smoothness, and flexibility.

Benefits

Enhances skin softness and smoothness through emollient action.

Promotes skin flexibility by supporting natural lipid structure.

Offers non-comedogenic conditioning suitable for daily use.

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
Individuals with dry or rough skin seeking conditioning.
People with known allergies to serine derivatives.
Those desiring support for skin's moisture retention.
Those sensitive to fatty acid esters.
Users of emollient-rich products for comfort.
Individuals preferring only plant-based ingredients.

Safety Notes

  • Considered low hazard with minimal risk of irritation.
  • Suitable for most skin types when used as directed.

Frequently Asked Questions about Palmitoyl Myristyl Serinate

What is Palmitoyl Myristyl Serinate?

A synthetic ester resembling skin ceramides, used as a conditioning emollient in cosmetics.

Is it safe for sensitive skin?

Yes, it carries a low hazard rating and low irritation potential.

Does it clog pores?

No, it has a comedogenic rating of zero.