Oligopeptide-1

What is Oligopeptide-1?

Oligopeptide-1 is a synthetic peptide composed of 53 amino acids, designed to mimic the sequence of human epidermal growth factor (EGF), a naturally occurring protein in skin cells. Produced via recombinant DNA technology using non-pathogenic organisms like yeast or bacteria, it falls under the category of signaling peptides in cosmetics. Primarily featured in serums, creams, and regenerative skincare products, it works by binding to epidermal growth factor receptors on keratinocytes and fibroblasts. This interaction supports cellular signaling pathways involved in skin renewal and barrier function, aiding in the preservation of hydration and structural resilience. Unlike larger proteins, its small size allows better formulation stability and skin surface activity, contributing to conditioning without deep penetration.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Roles in Formulation

This ingredient serves the following purposes in cosmetic formulations:

Skin conditioning agent
Maintains skin softness, smoothness, and flexibility.

Benefits

Supports skin softness by aiding moisture retention.

Promotes smoothness through enhanced cellular communication.

Helps maintain flexibility for resilient skin texture.

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
Individuals with dry or rough skin seeking conditioning.
Those with known peptide sensitivities.
People looking to support skin barrier resilience.
People allergic to biotech-derived ingredients.
Users of regenerative skincare routines.
Individuals with compromised skin barriers.

Safety Notes

  • Rated low hazard by safety assessments.
  • Non-comedogenic, suitable for acne-prone skin.

Frequently Asked Questions about Oligopeptide-1

What is Oligopeptide-1?

A 53-amino acid peptide mimicking human EGF, used for skin conditioning in cosmetics.

Is Oligopeptide-1 safe for daily use?

Safety data indicates low hazard and minimal irritation risk in formulations.

Does it clog pores?

It has a comedogenic rating of 0, making it non-pore-clogging.