Niacinamide Polypeptide

What is Niacinamide Polypeptide?

Niacinamide Polypeptide is a synthetic cosmetic ingredient where niacinamide, the amide form of vitamin B3, is conjugated to a polypeptide chain made of amino acids. This structure is commonly incorporated into skincare products like serums, creams, and lotions within the skin conditioning category. The polypeptide linkage aims to improve niacinamide's solubility, stability, and potential skin penetration compared to free niacinamide. In formulations, it works by interacting with skin lipids and proteins to support moisture retention and barrier integrity. Derived from biotechnological processes, it offers a stable alternative for delivering niacinamide benefits in multi-functional cosmetic blends, suitable for daily use across various skin types due to its mild profile.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Benefits

Supports skin's natural moisture balance.

Helps maintain barrier function.

Compatible with diverse formulations for conditioning.

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
Individuals seeking gentle conditioning agents.
Those with known sensitivity to niacinamide.
People with normal to oily skin types.
People allergic to polypeptides.
Users incorporating vitamin B3 derivatives routinely.
Individuals experiencing reactions to vitamin B3 forms.

Safety Notes

  • Rated low hazard by EWG assessments.
  • Non-comedogenic with rating of 0.

Frequently Asked Questions about Niacinamide Polypeptide

What is Niacinamide Polypeptide?

A niacinamide-peptide conjugate used as a skin conditioner in cosmetics.

Is it safe for sensitive skin?

It has a low hazard rating and is generally mild.

Does it clog pores?

It has a comedogenic rating of 0, indicating low risk.