Neohesperidin Dihydrochalcone

What is Neohesperidin Dihydrochalcone?

Neohesperidin dihydrochalcone is a semisynthetic flavonoid glycoside derived from neohesperidin, a natural compound extracted from the immature fruits of Seville bitter oranges (Citrus aurantium). This pale yellow powder exhibits intense sweetness, approximately 1,000 to 2,000 times that of sucrose, due to its dihydrochalcone structure formed via catalytic hydrogenation. In cosmetics, it primarily appears in oral hygiene products like toothpastes and mouthwashes, as well as lipsticks and balms. It functions by imparting a clean, sweet taste that boosts palatability, while also contributing subtle fruity or citrus-like notes to fragrances and effectively neutralizing off-odors or bitter aftertastes from other ingredients, thereby elevating the overall sensory appeal without adding calories.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →
PubChem View on PubChem →

Roles in Formulation

This ingredient serves the following purposes in cosmetic formulations:

Flavoring agent
Adds or adjusts taste and aroma in oral care and lip products, improving user acceptance while complementing the overall sensory profile.
Fragrance ingredient
Contributes scent character and/or masks base odors, shaping the overall sensory experience of the formula (subject to allergen and IFRA considerations).
Masking
Reduces perception of unpleasant odors or tastes by neutralizing them or covering them with more acceptable sensory notes.

Benefits

Enhances taste in oral products for improved daily use experience.

Masks unwanted odors, creating a more pleasant product profile.

Supports agreeable sensory notes in fragrances for lip and mouth items.

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
Individuals seeking better-flavored toothpastes or mouthwashes.
Those with known citrus flavonoid allergies.
Users of lip products desiring subtle sweetness.
Individuals sensitive to intense sweeteners.
People preferring natural-derived flavor enhancers in cosmetics.
People with rare oral sensitivities to glycosides.

Safety Notes

  • Rated low hazard by safety assessors with minimal absorption concerns.
  • Non-comedogenic and suitable for most skin types in rinse-off uses.

Frequently Asked Questions about Neohesperidin Dihydrochalcone

What is neohesperidin dihydrochalcone used for in cosmetics?

Primarily as a flavoring and masking agent in toothpastes, mouthwashes, and lip products to improve taste and scent.

Is it safe for daily use?

Assessed as low risk in cosmetics when used within standard concentrations.

Does it benefit skin directly?

Functions mainly for sensory enhancement rather than skin-active effects.