N-Hydroxysuccinimide

What is N-Hydroxysuccinimide?

N-Hydroxysuccinimide is a synthetic heterocyclic compound, chemically 1-hydroxy-2,5-pyrrolidinedione, with a five-membered ring structure containing nitrogen and oxygen. Produced through chemical synthesis, it belongs to the class of succinimide derivatives commonly used in cosmetics. As a skin conditioning agent, it appears in serums, creams, and eye-area products. In formulations, it interacts with the skin's surface layers, aiding in moisture retention and enhancing tactile qualities by supporting protein and lipid organization. This contributes to improved skin feel and resilience without contributing to pore blockage. Valued for its mild profile, it integrates well into multi-ingredient blends targeting texture refinement in daily skincare routines.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Roles in Formulation

This ingredient serves the following purposes in cosmetic formulations:

Skin conditioning agent
Maintains skin softness, smoothness, and flexibility.

Benefits

Supports skin softness and smoothness

Enhances skin flexibility and suppleness

Maintains hydration balance for better texture

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
People with dry or rough skin
Those with rare hypersensitivity to succinimide compounds
Individuals seeking improved skin texture
People preferring exclusively botanical ingredients
Users of conditioning-focused facial products
Individuals who experience irritation upon application

Safety Notes

  • Low overall hazard rating from safety assessments
  • Non-comedogenic, unlikely to clog pores

Frequently Asked Questions about N-Hydroxysuccinimide

What does N-Hydroxysuccinimide do in skincare?

It acts as a skin conditioning agent to maintain softness, smoothness, and flexibility.

Is N-Hydroxysuccinimide safe for daily use?

It has a low hazard profile and is suitable for most skin types in cosmetic products.

Does it clog pores?

No, it has a comedogenic rating of zero.