Methyl Acetylglycyrrhetinoyl Hydroxyprolinate
What is Methyl Acetylglycyrrhetinoyl Hydroxyprolinate?
Methyl Acetylglycyrrhetinoyl Hydroxyprolinate is a semi-synthetic compound derived from 18-beta-glycyrrhetinic acid, a triterpenoid from licorice root (Glycyrrhiza glabra), chemically modified by esterification with N-methyl hydroxyproline, an amino acid derivative. Classified as a skin conditioning agent in cosmetic formulations, it typically appears in moisturizers, serums, and anti-aging creams. This ingredient functions primarily as an emollient and humectant, helping to soften skin, enhance moisture retention, and support the skin's natural barrier. Its structure allows it to interact with skin lipids and proteins, promoting smoothness and suppleness without contributing to pore blockage, making it suitable for various skin types in leave-on products.
Benefits
Conditions skin for improved texture and softness
Supports moisture balance as an emollient
Non-comedogenic, ideal for clearer skin appearance
Who It's For
A quick guide for who this ingredient may suit (and who should be cautious).
| Who May Benefit | Who Should Avoid |
|---|---|
| Individuals with dry or dehydrated skin | People with known licorice allergies |
| Users of conditioning skincare routines | Those sensitive to triterpenoid compounds |
| Those preferring low-hazard cosmetic ingredients | Users avoiding synthetic derivatives |
Safety Notes
- Considered low hazard by safety assessments
- Minimal reports of adverse reactions in formulations
Frequently Asked Questions about Methyl Acetylglycyrrhetinoyl Hydroxyprolinate
What is Methyl Acetylglycyrrhetinoyl Hydroxyprolinate?
A semi-synthetic skin conditioner from licorice root's glycyrrhetinic acid and hydroxyproline, used to soften and hydrate skin.
Is it safe for daily use?
It has a low hazard profile and is suitable in cosmetic products for most skin types.
Does it clog pores?
No, it carries a comedogenic rating of 0, making it non-pore-clogging.