Isoquercitrin

Benefits
Antioxidant

What is Isoquercitrin?

Isoquercitrin, chemically quercetin 3-O-glucoside, is a natural flavonol glycoside extracted from plants like Sophora japonica buds, onions, and apples. This water-soluble derivative of quercetin offers improved stability for cosmetic use. Primarily categorized as an antioxidant in skincare products such as serums, creams, and lotions, it works by neutralizing free radicals through electron donation and inhibiting peroxidation reactions. This mechanism safeguards unsaturated oils, fragrances, and active compounds from degrading, preventing rancidity, odor changes, and discoloration during storage. In topical applications, it bolsters skin's barrier against environmental oxidants like pollution, supporting formulation integrity and skin resilience without contributing to pore clogging.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Roles in Formulation

This ingredient serves the following purposes in cosmetic formulations:

Antioxidant
Slows oxidation of oils, fragrances, and sensitive actives to improve shelf life and reduce rancidity or color change; sometimes also supports skin protection from oxidative stress.

Benefits

Provides antioxidant protection to maintain product stability and freshness

Supports skin defense against oxidative environmental stressors

Non-comedogenic, making it suitable for various skin types including acne-prone

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
People exposed to urban pollution or oxidative environments
Those allergic to flavonoids or quercetin-related compounds
Users of formulations with delicate oils and actives
People with sensitivities to plant extracts
Individuals seeking stable, long-shelf-life skincare products
Anyone noticing irritation upon patch testing

Safety Notes

  • Low hazard potential suitable for cosmetic use
  • Minimal risk of comedogenicity or pore clogging

Frequently Asked Questions about Isoquercitrin

What is isoquercitrin used for in skincare?

It functions as an antioxidant to stabilize ingredients and protect against oxidative stress.

Is isoquercitrin safe for daily use?

It has a low hazard rating and is generally suitable for cosmetic applications.

Does isoquercitrin clog pores?

It carries a comedogenic rating of 0, indicating low risk of pore clogging.