Hydroxypropylammonium Gluconate

What is Hydroxypropylammonium Gluconate?

Hydroxypropylammonium Gluconate is a synthetic ingredient derived from gluconic acid, produced by oxidizing glucose, and neutralized with hydroxypropylamine to form a water-soluble ammonium salt. It belongs to the category of chelating and buffering agents in cosmetics. In formulations, it functions by forming stable complexes with trace metal ions such as iron, copper, and calcium present in water or raw materials. This prevents metals from catalyzing oxidative reactions that could lead to product discoloration, rancidity, or emulsion breakdown. It also helps maintain optimal pH levels for product stability and skin compatibility, commonly appearing in cleansers, toners, serums, and moisturizers across rinse-off and leave-on categories.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Benefits

Supports product stability by chelating metal ions

Aids in maintaining balanced pH in formulations

Contributes to overall formula gentleness

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
People with sensitive skin seeking stable products
Those with rare allergies to gluconate salts
Users of water-based skincare items
People sensitive to amine derivatives
Individuals preferring mild preservative systems
Anyone experiencing unexplained reactions to chelators

Safety Notes

  • Considered safe for cosmetic use by regulatory bodies
  • Low potential for skin sensitization based on reviews

Frequently Asked Questions about Hydroxypropylammonium Gluconate

What does it do in skincare?

It chelates metals to prevent oxidation and adjusts pH for stability.

Is it safe for sensitive skin?

Yes, it has a low hazard rating and gentle profile.

Does it clog pores?

Rated non-comedogenic with zero rating.