Disodium Uridine Phosphate

What is Disodium Uridine Phosphate?

Disodium Uridine Phosphate is the disodium salt of uridine-5'-monophosphate, a ribonucleotide naturally present in cellular RNA across living organisms. Produced synthetically or via microbial fermentation, it belongs to the nucleotide family used in cosmetics. Primarily functioning as a skin conditioning agent-miscellaneous, it appears in serums, creams, and eye treatments within revitalizing and hydrating product lines. In formulations, it contributes to skin softening by aiding moisture balance and potentially supporting metabolic processes through phosphate donation, enhancing overall skin feel without altering structure. Cosmetic regulatory databases list it for topical use at trace levels, compatible with sensitive skin routines due to its biochemical mildness.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Benefits

Conditions skin for improved softness and smoothness.

Aids in maintaining hydration levels.

Compatible with formulations for daily skin care.

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
People with dry or dehydrated skin.
Anyone with known nucleotide sensitivities.
Individuals incorporating revitalizing products.
People experiencing reactions during patch testing.
Those preferring gentle conditioning ingredients.
Those preferring to avoid phosphate-containing compounds.

Safety Notes

  • Rated low hazard by safety assessments.
  • Non-comedogenic with minimal irritation reports.

Frequently Asked Questions about Disodium Uridine Phosphate

What is Disodium Uridine Phosphate?

A disodium salt of a natural ribonucleotide used as a skin conditioning agent in cosmetics.

Is it irritating to skin?

Evidence indicates low irritation potential for most users.

Does it clog pores?

It has a comedogenic rating of 0, suitable for acne-prone skin.