Dextran Sulfate

What is Dextran Sulfate?

Dextran Sulfate is an anionic polymer derived from dextran, a branched polysaccharide made of glucose monomers. Dextran originates from bacterial fermentation of sucrose by Leuconostoc mesenteroides. Sulfation introduces sulfate groups, enhancing its solubility and binding capacity. In cosmetics, it falls under polymers and conditioning agents, commonly used in skincare emulsions, powders, and solid formats. It works by linking solid particles for better cohesion, aiding the formation of stable tablets, compacts, or sticks with improved durability and application. As a skin conditioner, it deposits a lightweight film that supports moisture retention, promoting a smoother, more pliable skin surface. Its compatibility with water-based systems ensures even distribution and pleasant texture in daily-use products like creams and serums.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →
PubChem View on PubChem →

Roles in Formulation

This ingredient serves the following purposes in cosmetic formulations:

Binder
Helps hold solid ingredients together to form cohesive tablets, compacts, or sticks, improving pressability, integrity, and wear of the finished product.
Skin conditioning agent
Maintains skin softness, smoothness, and flexibility.
Binding
Provides cohesion by helping ingredients stick together, improving the strength and integrity of pressed powders, tablets, or solid bars.

Benefits

Enhances formulation stability by binding ingredients together.

Supports skin softness and flexibility through conditioning action.

Maintains clear pores with zero comedogenic rating.

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
Individuals seeking smoother skin texture from conditioning agents.
Those with rare polysaccharide sensitivities.
Users of powder or solid cosmetics for better product wear.
Individuals preferring preservative-free or minimalistic products.
People preferring stable, cohesive skincare formulations.
People unsure about bacterial-derived ingredients without patch testing.

Safety Notes

  • Consistently low hazard rating from safety assessments.
  • Minimal irritation potential in cosmetic concentrations.

Frequently Asked Questions about Dextran Sulfate

What is Dextran Sulfate used for in skincare?

It acts as a binder to hold ingredients together and a conditioner to maintain skin smoothness.

Is Dextran Sulfate safe for daily use?

Safety reviews indicate low hazard and irritation potential in cosmetics.

Does it affect pore appearance?

It has a comedogenic rating of 0, posing no clogging risk.