CI 45380 (D&C Red No. 21 Or 22) Lake
What is CI 45380 (D&C Red No. 21 Or 22) Lake?
CI 45380 Lake, known as D&C Red No. 21 Lake, is a synthetic pigment created by adsorbing the dye D&C Red No. 21—chemically tetrabromofluorescein disodium salt—onto a substrate like aluminum hydroxide. This process renders it insoluble in water and oils, ideal for anhydrous cosmetics. As a colorant, it functions by dispersing evenly in formulations to impart a bright, medium red shade without dissolving or migrating. Commonly found in lipsticks, rouges, eyeshadows, and nail polishes, it adheres to skin surfaces for durable pigmentation. Its lake form enhances compatibility with waxy or oily bases, preventing bleeding or color shifts during application or wear.
Benefits
Provides vivid, consistent red coloration in makeup products.
Offers stability in oil-based formulas without leaching.
Enhances visual appeal of cosmetics with surface-bound pigment.
Who It's For
A quick guide for who this ingredient may suit (and who should be cautious).
| Who May Benefit | Who Should Avoid |
|---|---|
| Makeup enthusiasts desiring intense red tones in lip and cheek products. | Those with sensitivities to fluorescein-based dyes. |
| Users of long-wear cosmetics needing fade-resistant color. | People experiencing contact reactions to synthetic pigments. |
| Individuals with typical tolerance to certified color additives. | Consumers opting for dye-free or natural ingredient formulas. |
Safety Notes
- Certified for cosmetic use by regulators when meeting purity standards.
- Rare potential for sensitization; individual patch testing advised.
Frequently Asked Questions about CI 45380 (D&C Red No. 21 Or 22) Lake
What is CI 45380 Lake?
An insoluble synthetic red pigment made from D&C Red No. 21 dye on an aluminum base, used for coloring cosmetics.
Is CI 45380 Lake comedogenic?
Rated 0, indicating no known pore-clogging potential.
Can it cause irritation?
Generally low irritation risk in approved uses, though sensitivities vary.