Alanyl Glutamine

Benefits
MoisturizingSoftening

What is Alanyl Glutamine?

Alanyl Glutamine is a synthetic dipeptide created by bonding the amino acids alanine and glutamine. It falls under skin conditioning agents in cosmetics, primarily functioning as a humectant and emollient. As a humectant, it pulls water from the environment into the skin's upper layers, promoting hydration and helping to keep the stratum corneum plump. Its emollient action softens skin by filling microscopic gaps on the surface, enhancing smoothness and reducing dryness. Typically incorporated into moisturizers, lotions, serums, and cleansers at low levels, it supports the skin's moisture retention without forming a heavy barrier. The compact dipeptide structure allows for efficient absorption, aiding in maintaining skin flexibility and comfort during daily use. Derived from fundamental building blocks of proteins, it mimics natural moisturizing factors found in skin.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Roles in Formulation

This ingredient serves the following purposes in cosmetic formulations:

Humectant
Attracts and holds water in the stratum corneum, boosting hydration and plumpness; commonly used in moisturizers, cleansers, and hair conditioners.
Emollient
Softens and smooths skin by filling in surface roughness and improving slip; can also help reduce moisture loss when paired with occlusives and film formers.
Skin conditioning agent
Maintains skin softness, smoothness, and flexibility.

Benefits

Boosts skin hydration by attracting and holding water.

Softens skin texture for a smoother feel.

Supports skin conditioning for maintained flexibility.

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
People with dry or dehydrated skin needing extra moisture.
Those with rare allergies to amino acid derivatives.
Individuals seeking softer, plumper skin from daily products.
People sensitive to peptide-based ingredients.
Users of humectant-based moisturizers and serums.
Individuals who prefer anhydrous formulations.

Safety Notes

  • Considered low hazard with minimal risk of irritation.
  • Non-comedogenic, unlikely to clog pores.

Frequently Asked Questions about Alanyl Glutamine

What does Alanyl Glutamine do in skincare?

It acts as a humectant to hydrate skin and an emollient to soften texture.

Is Alanyl Glutamine irritating?

It has low irritation potential based on safety assessments.

Can it be used on acne-prone skin?

Yes, its comedogenic rating of 0 suggests low pore-clogging risk.