Acetylaringyltryptophyl Diphenylglycine

What is Acetylaringyltryptophyl Diphenylglycine?

Acetylarginyltryptophyl Diphenylglycine is a synthetic oligopeptide featuring an acetylated chain of arginyl, tryptophyl, and diphenylglycine components. Classified as a skin conditioning agent in cosmetics, it appears in facial serums, creams, and anti-aging formulations. This ingredient functions by aiding skin barrier support and promoting a smoother texture through molecular interactions that enhance moisture retention and suppleness. Its chemical structure mimics aspects of natural peptides, enabling compatibility in water-based and emulsion products. Regulatory bodies and databases like EWG assign it a low hazard rating of 1, reflecting minimal concerns across toxicity, irritation, and allergenicity endpoints. With a comedogenic rating of 0, it poses low risk of pore clogging. Primarily used in leave-on products at trace levels, it contributes to overall formulation stability and sensory feel without reported restrictions in major cosmetic regulations.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Benefits

Supports skin conditioning for improved texture

Non-comedogenic, suitable for blemish-prone skin

Low hazard rating enhances product safety profile

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
People seeking peptide-based conditioners
Those with rare peptide sensitivities
Individuals with oily or acne-prone skin
People preferring fully natural formulations
Users prioritizing low-risk cosmetic ingredients
Individuals not patch-testing new ingredients

Safety Notes

  • EWG rates it 1, indicating low overall hazard
  • No known comedogenic effects (rating 0)

Frequently Asked Questions about Acetylaringyltryptophyl Diphenylglycine

What role does Acetylarginyltryptophyl Diphenylglycine play in skincare?

It serves as a skin conditioning agent in creams and serums to support texture and moisture.

Is it safe for daily use?

Yes, with a low EWG hazard score of 1 and zero comedogenic rating.

Can it clog pores?

No, it has a comedogenic rating of 0, making it pore-friendly.