Acetyl Tripeptide-1

What is Acetyl Tripeptide-1?

Acetyl Tripeptide-1 is a bioactive synthetic tripeptide produced through peptide synthesis, featuring an acetylated N-terminus and a sequence mimicking natural signaling molecules. It belongs to the category of conditioning and firming agents in cosmetics, particularly anti-aging formulations like serums, creams, and eye treatments. Functionally, it operates as a messenger peptide that binds to receptors on fibroblasts in the dermis, stimulating production of extracellular matrix proteins including collagen types I, III, and IV, laminin 5, and fibronectin. This activity reinforces the dermal-epidermal junction, aiding skin structure integrity. Soluble in water, it integrates easily into aqueous-based products and remains stable across typical cosmetic pH levels, enabling consistent performance in daily skincare routines.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Roles in Formulation

This ingredient serves the following purposes in cosmetic formulations:

Skin conditioning agent
Maintains skin softness, smoothness, and flexibility.

Benefits

Supports maintenance of skin softness and smoothness.

Promotes skin flexibility and suppleness.

Contributes to overall skin conditioning effects.

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
Individuals noticing reduced skin smoothness.
Those with known peptide sensitivities.
People with skin lacking flexibility.
Individuals avoiding synthetic ingredients.
Users incorporating conditioning agents into routines.
People experiencing reactions to similar peptides.

Safety Notes

  • Considered low hazard for cosmetic use.
  • Non-comedogenic, unlikely to clog pores.

Frequently Asked Questions about Acetyl Tripeptide-1

What is Acetyl Tripeptide-1?

A synthetic tripeptide used as a skin conditioning agent in cosmetics to maintain softness and flexibility.

Is it safe for daily use?

Rated low hazard and non-comedogenic, suitable for most in formulated products.

Does it clog pores?

Has a comedogenic rating of 0, unlikely to contribute to pore blockage.