Acetyl Tetrapeptide-40

What is Acetyl Tetrapeptide-40?

Acetyl Tetrapeptide-40 is a synthetically produced short-chain peptide made from four amino acids, featuring an acetyl group at one end for stability. It falls under skin conditioning agents in cosmetic formulations, typically appearing in leave-on products like creams, serums, and lotions aimed at maintaining skin comfort. This ingredient functions through biomimetic action, interacting with skin receptors similar to natural peptides to support homeostasis and reduce reactivity from environmental or formulation stressors. Official databases such as the EU CosIng classify it as a miscellaneous skin conditioning agent without usage limits or warnings. Assessments from safety panels highlight its mild nature, aligning with low concern ratings from hazard evaluations. Its inclusion helps enhance product gentleness, particularly in multi-active blends.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 1 View on EWG →

Benefits

Supports skin conditioning in formulations

Exhibits low comedogenic potential (rating 0)

Carries a low hazard score from verified assessments

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
Individuals with sensitive skin types
People with known peptide sensitivities
Users incorporating multiple active ingredients
Those experiencing reactions to similar synthetic actives
Those seeking gentle daily conditioning agents
Individuals preferring fully natural ingredient lists

Safety Notes

  • Rated low hazard (EWG 1) with limited data concerns
  • No known regulatory restrictions in major markets

Frequently Asked Questions about Acetyl Tetrapeptide-40

What is Acetyl Tetrapeptide-40?

A synthetic tetrapeptide serving as a skin conditioning agent in cosmetics.

Is it safe for sensitive skin?

It has a low hazard rating and non-comedogenic profile, suitable for gentle use.

What role does it play in products?

Functions to condition skin, often in serums and creams.