2-Amino-4-Hydroxyethylaminoanisole Sulfate

What is 2-Amino-4-Hydroxyethylaminoanisole Sulfate?

2-Amino-4-Hydroxyethylaminoanisole Sulfate is a synthetic organic compound, specifically the sulfate salt of 2-amino-4-(2-hydroxyethylamino)anisole, classified among aromatic amine derivatives. It serves as a coupler in oxidative hair coloring systems, primarily in permanent dyes. During application, it interacts with primary dye intermediates and an oxidizing agent like hydrogen peroxide. This reaction generates polymeric dye molecules that diffuse into the hair shaft, binding within the cortex to deliver stable, wash-resistant coloration. Commonly incorporated into professional and consumer hair dye formulations at regulated levels, it enables a spectrum of shades from browns to reds by facilitating controlled oxidation and coupling processes. Its role is confined to hair fiber modification, not direct pigmentation or skin application.

Comedogenic Rating 0/5 Low risk of clogging pores
EWG Safety Rating 3 View on EWG →
PubChem View on PubChem →

Roles in Formulation

This ingredient serves the following purposes in cosmetic formulations:

Hair colorant
Delivers hair color through dyes and/or pigments (direct or oxidative systems), producing a visible shade change and supporting coverage and longevity.
Hair dyeing
Supports chemical color change of hair (e.g., oxidative dye development or bleaching), enabling shade transformation through controlled reactions on the fiber.

Benefits

Facilitates creation of durable, multi-tonal hair shades through oxidative reactions.

Aids in achieving even coverage for varied hair types in dye systems.

Supports color stability against shampooing and environmental factors.

Who It's For

A quick guide for who this ingredient may suit (and who should be cautious).

Who May Benefit Who Should Avoid
People undergoing permanent hair coloring for shade changes.
Those with allergies to hair dye components.
Users seeking customized, long-wear color results.
People experiencing scalp sensitivity or dermatitis.
Individuals applying oxidative dyes for gray blending.
Individuals sensitive to aromatic amine structures.

Safety Notes

  • Potential for allergic contact dermatitis requires pre-application patch testing.
  • Regulated for use in hair dyes with established concentration restrictions.

Frequently Asked Questions about 2-Amino-4-Hydroxyethylaminoanisole Sulfate

What role does it play in hair products?

Acts as a coupler in oxidative hair dyes to develop permanent colors via chemical reactions.

Is it found in all hair dyes?

Primarily in permanent oxidative formulations, not temporary or direct dyes.

How to minimize risks?

Conduct a patch test 48 hours prior and follow product instructions.